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Dacarbazine ( da-KAR-ba-zeen ) (DTIC) What is this medication used for? Dacarbazine destroys cancer cells by interfering with their growth cycle.
What does it look like? • Liquid How is it given?
Special instructions: • This medicine can cause irritation if it leaks out of the vein. Tell the person giving the medicine if a burning sensation or pain occurs while it is being administered. If the skin becomes red or swollen, call a healthcare provider. If a blister or scab appears at the injection site, do not pop it or pick at it. • This medicine can cause skin sensitivity, so exposure to sunlight should be avoided. • In utero exposure may cause fetal harm.
• Into the vein (IV) or venous access device What are the common side effects? • Nausea or vomiting • Hair loss (alopecia) • Flu-like symptoms (fever, aches, or tiredness) • Pain at the injection site • Low blood counts 2–4 weeks after treatment What are the less common side effects? • Metallic taste in the mouth during the infusion • Changes in liver function tests
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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