2025 Medication Fact Sheets Full Document_100825

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Cladribine ( CLAD-rih-been ) (2-CdA, Leustatin®) What is this medication used for? Cladribine slows or stops the growth of cancer cells.

What does it look like? • Liquid How is it given?

Special instructions: • Blood tests will be done to check blood cell counts. • In utero exposure may cause fetal harm.

• Into the vein (IV) or venous access device What are the common side effects? • Low blood counts (white blood cells, red blood cells, platelets) • Fever, especially when blood counts are low • Feeling tired (fatigue, malaise) What are the less common side effects? • Mild nausea • Vomiting • Loss of appetite • Skin rash • Dizziness • Difficulty sleeping or inability to sleep (insomnia) • Diarrhea • Headache • Cough • Muscle aches or pains • Infections

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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