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Cisplatin ( SIS-pluh-tin ) (Cis-Platinum, CDDP, Platinol®) What is this medication used for? CCisplatin is used to destroy cancer cells. It interferes with their growth cycle.
What does it look like? • Liquid How is it given? • Into the vein (IV) or a venous access device What are the common side effects? • Nausea or vomiting, immediate and delayed • Loss of appetite • Hearing loss, most often in the higher tones • Low blood counts in 2–4 weeks • Low level of magnesium in the blood What are the less common side effects? • Numbness and tingling in fingers and toes (peripheral neuropathy) • Low levels of sodium, calcium, potassium, or phosphorus in the blood • Metallic taste in the mouth • Problems with balance • Ringing in the ears What are the rare side effects?
Special instructions: • This medicine may cause nausea and vomiting that may last for 1 week. Medications or IV fluid may be given to prevent nausea and vomiting. • This medicine may cause kidney damage. Fluid intake and urine output will be closely monitored before, during, and after treatment. • Blood tests will be done to check the levels of electrolytes, especially magnesium, in the blood. • Electrolyte supplements may be prescribed to be taken by mouth. • A hearing test will be done before receiving treatment and at certain times during treatment. • Kidney function will be tested before this treatment is given and at certain times during treatment. • Consult your healthcare provider before becoming pregnant, fathering a child, or breastfeeding. It may be important to use birth control while taking this medicine and for several months after treatment is completed. • In utero exposure may cause fetal harm.
• Allergic reactions • Kidney damage
• Deafness • Seizures • Decrease in muscle or nerve reflexes
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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