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Brentuximab ( bren-TUX-i-mab ) (Adcetris®) What is this medication used for? Brentuximab is a type of targeted medication known as an antibody-drug conjugate. These destroy cancer cells by locating and binding to them and releasing a medicine that disrupts cell growth..
• Infusion reactions (rash, chills, difficulty breathing, or swelling of the face, mouth, and throat) • Increase in blood sugar (increased thirst, confusion, urinary frequency, or fatigue)
What does it look like? • Liquid How is it given?
• Into the vein (IV) or venous access device What are the common side effects? • Feeling tired (fatigue, malaise) • Fever • Numbness and tingling in hands and feet (peripheral neuropathy) • Rash • Chills • Nausea and vomiting • Diarrhea • Low blood counts (red blood cells, platelets, white blood cells) • Cough What are the less common side effects?
• Red or blistering skin • Red or irritated eyes • Sores in the mouth, throat, or nose Special instructions:
• Notify your healthcare provider immediately symptoms of an infusion reaction are experienced during or within 24 hours after infusion • The dosage may be adjusted or discontinued based on severity of peripheral neuropathy symptoms • Notify your healthcare provider immediately if any of the following are experienced: red or blistering skin; red or irritated eyes; sores in the mouth, throat, or nose; or high blood sugar symptoms (increased thirst, confusion, urinary frequency, or fatigue) • In utero exposure may cause fetal harm.
• Heart rhythm changes • Changes in breathing
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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