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Vorinostat ( voh-RIN-oh-stat ) (Zolinza®) What is this medication used for? Vorinostat is used to treat leukemias and cutaneous T-cell lymphoma.
What does it look like? • Capsules • Liquid How is it given? • By mouth (oral or po) What are the common side effects? • Mild Nausea or vomiting • Diarrhea • Low blood counts • Feeling of tiredness (fatigue, malaise) • Dizziness What are the less common side effects? • Cough • Decreased appetite and weight loss • Hair loss (alopecia) • Swelling of arms, legs, hands, or feet (peripheral edema) • Changes in kidney and liver function tests • Dehydration
Special instructions: • Do not open or break the capsules. If the capsules cannot be swallowed whole, tell your healthcare provider so the pharmacy can make a liquid suspension. • Take the medicine with food and plenty of fluids – at least 2 liters of water a day to keep from getting dehydrated. Avoid becoming dehydrated or overheated during exercise or in the summer months. • It is important to use birth control while taking this medicine and for 30 days after the last dose.
• Muscle pain or weakness • High blood sugar levels • Dry mouth • Fever
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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