2025 Medication Fact Sheets Full Document_100825

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Ursodiol ( er-so-DYE-all ) (Urso 250®, Urso Forte®, Actigall®) What is this medication used for? Ursodiol is used to treat or prevent gallstones. It works by decreasing the production of cholesterol and dissolving the cholesterol in bile to prevent gallstones and decrease toxic levels of bile acids.

What does it look like? • Capsule

Special instructions: • Store this medicine at room temperature in a dry place. • Tablets may be broken in half. • Take this medicine with food. • Do not take antacids within 2 hours before or after taking ursodiol. • Do not give two doses at the same time or extra doses.

• Tablet • Liquid How is it given? • By mouth (oral or po) What are the common side effects? • Upset stomach • Headaches What are the less common side effects?

• Allergic reaction, which may include rash; itching (pruritis); and red, swollen, blistered, or peeling skin, with or without fever • Vomiting • Dizziness • Constipation or diarrhea • Back pain • Stomach (abdominal) pain or heartburn (indigestion) • Hair loss (alopecia) • Painful urination

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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