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Rho(D) Immune Globulin ( roe dee im-YOON GLOB-yoo-lin ) (WinRho® SDF, RhoGAM) What is this medication used for? Rho(D) immune globulinis used in the treatment of immune thrombocytopenia (also called ITP).
What does it look like? • Liquid How is it given?
Special instructions: • Your healthcare provider will look for antibodies to the red blood cells before prescribing rho(D) immune globulin because the administration could result in severe breakdown of red blood cells (hemolysis). • Call a healthcare provider immediately if shaking, fever, chills, back pain, decreased urine production or persistent dark urine, dark or black stools, or shortness of breath develop after this medication is administered. • Although rho(D) immune globulin is generally infused over 3–5 minutes, side effects may be reduced by infusing the medicine over a longer period of time. • After administration, a blood test and urinalysis will be performed to monitor for side effects. • Your healthcare provider may suggest taking another medication (for example, acetaminophen or diphenhydramine) before rho(D) immune globulin to reduce side effects.
• Into the vein (IV) or venous access device What are the common side effects? • Low red blood cell counts (low hemoglobin, anemia) • Low platelet count (thrombocytopenia) • Low white blood cell counts (neutropenia)Headache • Chills or fever • Dark pink or orange urine • Pain at the injection site • Low or high blood pressure during the infusion • Nausea • Vomiting • Diarrhea • Rash What are the less common side effects? • Decreased urine production • Swelling in the hands, feet, mouth, or tongue (allergic reaction) • Shortness of breath • Changes in kidney function
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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