2025 Medication Fact Sheets Full Document_100825

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Paclitaxel ( pak-lih-TAKS-el ) (Taxol®, Onxol®) What is this medication used for? Paclitaxel is used to treat many types of solid tumors.

What does it look like? • Liquid How is it given?

What are the less common side effects? • Swelling of arms, legs, hands, or feet (peripheral edema) • Changes to liver function tests • Low heart rate (bradycardia) or abnormal heart rhythm • Mouth sores (mucositis) Special instructions: • Other medications are often given to help prevent allergic reaction. Notify a healthcare provider if any shortness of breath, wheezing, cough, or hives are experienced during the paclitaxel infusion. • A healthcare provider will check heart rate and blood pressure frequently to check that they do not become low during the infusion. • Notify your healthcare provider if swelling, burning, or redness occurs at the IV site during infusion.

• Into the vein (IV) or venous access device What are the common side effects? • Hypersensitivity reaction • Aches and pains in muscles (myalgia) • Joint pain (arthralgia) • Numbness or tingling in hands and feet (peripheral neuropathy) • Hair loss (alopecia) • Nausea and vomiting • Diarrhea • Low red blood cell, white blood cell, and platelet counts (pancytopenia) • Swelling, redness, or burning at infusion site

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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