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Oxaliplatin ( oks-al-ih-PLA-tin ) (Eloxatin®, Dacplat®, Elplat®, Dacotin®) What is this medication used for? This medicine is used to treat colon or rectal cancer. It may be used to treat solid tumors such as neuroblastoma or non-Hodgkin lymphoma which have not responded to standard chemotherapy.
What does it look like? • Liquid How is it given?
Special instructions: • This medicine may cause an allergic reaction. Notify a healthcare provider of any shortness of breath, cough, wheezing, or hives during infusion. • Avoid drinking or eating anything cold; use a blanket during infusion; wear warm clothing, cover mouth and face during cold weather, wear gloves when using refrigerator until sensitivities are resolved.
• Into the vein (IV) or venous access device What are the common side effects? • Increased sensitivity to cold, which can cause jaw spasms; a tingling sensation or numbness in the mouth, throat, arms, and legs; or, rarely, shortness of breath • Stomach (abdominal) cramps or pain • Diarrhea • Mouth sores (mucositis) • Tiredness (fatigue) • Loss of appetite (anorexia) • Numbness and tingling in hands and feet (peripheral neuropathy) What are the less common side effects? • Headache • Constipation (hard stools) • Heartburn • Change in taste • Rash • Swelling or puffiness (edema) • Severe allergic reaction (anaphylaxis; rare; may include hives, cough, wheezing, and shortness of breath) • Muscle tissue breakdown (rhabdomyolysis)
• Call a healthcare provider if diarrhea occurs • In utero exposure may cause fetal harm.
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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