2025 Medication Fact Sheets Full Document_100825

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Nelarabine ( nel-AY-ruh-been ) (Arranon®) What is this medication used for? Nelarabine is used to treat T-cell leukemia and T-cell lymphoma.

What does it look like? • Liquid How is it given?

Special instructions: • Notify your healthcare provider if any of the following symptoms occur: seizures, confusion,r extreme sleepiness; inability to drink enough fluids or signs of dehydration such as dry mouth, dark urine, decreased amount of urine, or dizziness; or swollen feet or ankles • Continue regular activities as much as possible. • In utero exposure may cause fetal harm.

• Into the vein (IV) or venous access device What are the common side effects?

• Low red blood cell count (low hemoglobin, anemia) • Increased risk of infection, especially when white blood cell counts are low • Nausea • Numbness, tingling, or pain in the arms and legs (peripheral neuropathy) • Feeling tired (fatigue, malaise) What are the less common side effects? • Diarrhea or constipation • Vomiting • Sores in mouth and throat (mucositis) • Swelling of arms or legs (edema) • Fever • Loss of appetite • Neurological symptoms (Muscle weakness or spasms, dizziness, confusion, headache, trouble with memory, difficulty walking and talking, weakness, abnormal body movements, seizures, altered mental state

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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