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Irinotecan ( eye-rin-oh-TEE-can ) (Camptosar®) What is this medication used for? Irinotecan destroys cancer cells by interfering with their growth cycle. What does it look like? • Liquid How is it given? • Into the vein (IV) or venous access device • By mouth (oral or po) What are the common side effects? • Severe diarrhea, which may cause dehydration and changes in levels of electrolytes (sodium and potassium) • Low white blood cell counts (neutropenia) • Sweating • Fever • Increased production of saliva • Nausea and vomiting • Loss of appetite (anorexia) • Stomach (abdominal) pain and cramping • Hair loss (alopecia) • Mouth sores (mucositis)
What are the less common side effects? • Feeling tired (fatigue, malaise) • Changes in liver and kidney function tests • Constipation • Pain at injection site • Rash • Itching (pruritis) • Redness and warmth in the face Special instructions:
• Diarrhea may occur even after stopping this medicine. • It is important to follow your healthcare provider’s instructions to take loperamide (Imodium®) at onset of diarrhea. • Call your healthcare provider if diarrhea persists or there are signs of dehydration such as decreased urine output, no tears when crying, dry mouth, or cracked lips.
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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