2025 Medication Fact Sheets Full Document_100825

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Intravenous Immune Globulin ( in-tra-VEE-nuss i-MYUN GLOB-yoo-lin ) (intravenous immunoglobulin, IVIG, immunoglobulin G) (Gammagard Liquid®, Gamunex ® -C, Hizentra®) What is this medication used for?

Intravenous immune globulin (IVIG) is a collection of antibodies that may help prevent some viral and bacterial infections. Your body may not be making IVIG on its own. IVIG also can block antibodies that destroy platelets, the part of your blood that helps stop bleeding.

What does it look like? • Liquid How is it given?

Special instructions: • Vital signs are taken frequently throughout the infusion to monitor for side effects. • If chills, difficulty breathing, tightness in the chest, nausea, or vomiting occur, tell the person giving the infusion or your healthcare provider. • Another medication may be given before IVIG to prevent fevers and chills.

• Into the vein (IV) or venous access device • Under the skin (subcutaneous or subq) What are the common side effects?

• Chills • Fever • Nausea • Headache • Irritation where the drug is given (if subcutaneous) • Back pain • Cramps • Flushing What are the less common side effects? • Allergic reaction, which may include chills, difficulty breathing, hives, and tightness in the chest • Dizziness

• Low blood pressure • Inability to pass urine • Change in how much urine is passed • Blood in urine • Swelling (edema) • Blood clots

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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