2025 Medication Fact Sheets Full Document_100825

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Interferon ( in-tur-FEER-on ) (Alpha, Beta, Gamma) What is this medication used for? Interferon activates the immune system by stimulating T-lymphocytes (a type of white blood cell) to kill tumor cells.

What does it look like? • Liquid How is it given? • Under the skin (subcutaneous or subq) • Into a muscle (IM) • Into a vein (IV) What are the common side effects? • Low-grade fever and chills • Flu-like symptoms, including headache, muscle aches, and tiredness

What are the rare but serious side effects? • Kidney damage Special instructions:

• The first dose of this medicine will be given in the hospital. If there is no allergic reaction, this medicine can be given at home. • Acetaminophen may be given before interferon to decrease fevers and headache. • Notify your healthcare provider immediately if neurologic side effects occur, such as dizziness, inability to walk normally (gait disturbance), or changes in mental status. • Blood tests will be performed to check blood counts, liver function, and kidney function. • Drink plenty of fluids while taking interferon. • In utero exposure may cause fetal harm.

• Changes to liver function tests • Redness at the injection site

• Skin rash • Headache • Feeling of tiredness (fatigue, malaise) What are the less common side effects? • Nausea, vomiting, and diarrhea • Allergic reaction (for example, difficulty breathing or low blood pressure) • Confusion

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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