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Ifosfamide ( eye-FOSS-fuh-mide ) (Ifex®) What is this medication used for? Ifosfamide destroys cancer cells by interfering with their growth cycle.
What does it look like? • Liquid How it is given?
Special instructions: • This medicine may cause bladder irritation. Fluid intake and urine output will be closely monitored before, during, and after Ifosfamide is given. A medicine called mesna (Mesnex®) will be given to help protect the bladder. • Call a healthcare provider if urination is painful or blood appears in the urine. • Consult your healthcare provider before becoming pregnant, fathering a child, or breastfeeding. It may be important to use birth control while taking this medicine and for several months after treatment is completed. • In utero exposure may cause fetal harm.
• Into the vein (IV) or venous access device What are the common side effects? • Nausea or vomiting • Decreased kidney function • Inability to father children (infertility) in males, which may be temporary or permanent • Hair loss (alopecia) • Low blood cell counts 1–2 weeks after treatment What are the less common side effects? • Blood in the urine and bladder irritation • Changes in liver function tests • Drowsiness • Constipation or diarrhea • Infertility in females • A new cancer, such as leukemia, resulting from treatment (secondary malignancy) • Heart damage • Confusion, dizziness, disorientation, or hallucinations • Blurred vision
Notes from Your Healthcare Team
Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.
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