2025 Medication Fact Sheets Full Document_100825

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Aminocaproic Acid ( uh-MEEN-oh-cuh-PRO-ick AH-sid ) (Amicar®) What is this medication used for? Aminocaproic acid slows the breakdown of blood clots, which helps prevent rebleeding.

What does it look like? • Syrup • Tablet • Liquid solution How is it given? • By mouth (syrup or tablet)

Special instructions: • This medicine should not be given to patients who have blood in their urine because it may cause clots in their kidneys. • Aminocaproic acid is not recommended for newborns. • Avoid rapid infusion because this can cause low blood pressure and a slow or abnormal heart rate. • This medicine may be associated with neurological symptoms (e.g., confusion, dizziness, hallucinations, weakness) if it is used to treat certain types of bleeding in the head. • Give exactly on time as prescribed by your healthcare provider. Call your healthcare provider if a dose is missed. • Call your healthcare provider immediately if you notice swelling of the hands or face, swelling or tingling in the mouth or throat, blood in the urine, chest pain, shortness of breath, coughing up of blood, confusion, muscle weakness, or dark urine. • Aminocaproic acid should not be given with bypassing agents such as prothrombin complex concentrates (PCCs), activated prothrombin complex concentrates (aPCCs or FEIBA®), and activated recombinant factor VIIa (NovoSeven®).

• Into the vein (IV) or venous access device What are the common side effects? • Abdominal pain • Diarrhea • Nausea or vomiting What are the less common side effects? • Clotting • Abnormal blood counts (e.g., low white blood cell or platelet counts) • Muscle weakness • Local skin reaction at injection site (phlebitis) • Headache, dizziness, or confusion • Slow or abnormal heart rate

Notes from Your Healthcare Team

Not all of the possible side effects of this medicine and precautions related to taking it are covered in this information sheet. For a complete list of side effects and precautions, ask your healthcare professional (doctor, nurse, pharmacist) for a manufacturer’s package insert or another reference.

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