Confidential
Activated Prothrombin Complex Concentrate: Anti-Inhibitor Coagulant Complex ( an-TEE in-HI-bi-tor coe-AG-yoo- lant KOM-pleks ) (FEIBA) How does this medicine work? This medicine works by fixing the damaged thrombin (a protein in the blood that causes the clotting of blood). It helps control spontaneous bleeding episodes or prevents bleeding episodes after surgeryin patients with hemophilia Aand Bwho have developed an antibody (inhibitor). What does it look like? Liquid solution How is it given?
Into the vein (IV) or venous access device What are the common side effects? Pain at the injection site What are the less common side effects? Low blood pressure Flushing Cough
Allergic reaction Rash or itchy skin Increased heart rate Abdominal pain Stroke Special instructions: Infuse at a rate of no more than 2 units/kg/min. If the medicine is given too quickly, it can cause headaches, flushing, changes in blood pressure, or an increased heart rate. The medicine should be stored at room temperature prior to reconstitution. After reconstitution, it should be stored at room temperature and used within 3 hours.
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